SCHEMBL29657355

SCHEMBL29657355

CNC(=N)NCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.61

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 18/20 0.61
▸ ECE1 P42892 1/20 0.55
▸ GHSR Q92847 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3497693 0.93 KISS1R (0.62) KISS1RECE1GHSR
SCHEMBL21851621 0.93 KISS1R (0.65) KISS1RECE1
SCHEMBL29872703 0.92 KISS1R (0.64) KISS1RECE1GHSR
SCHEMBL31718765 0.92 KISS1R (0.67) KISS1RECE1
SCHEMBL29851826 0.91 KISS1R (0.64) KISS1RECE1
SCHEMBL29657322 0.90 KISS1R (0.65) KISS1RECE1
SCHEMBL14685608 0.90 KISS1R (0.65) KISS1RECE1
SCHEMBL29871835 0.87 KISS1R (0.60) KISS1RGHSR
SCHEMBL15896470 0.86 KISS1R (0.72) KISS1R
SCHEMBL31718762 0.86 KISS1R (0.78) KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3650464-B1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND SHANGPHARMA INNOVATION INC (US) 2025-11-05 — — EP disclosed
US-11807660-B2 Peptide compound and application thereof, and composition containing peptide compound XDCEXPLORER (SHANGHAI) CO., LTD. (CN) 2023-11-07 — — US disclosed
US-11427615-B2 Peptide compound and application thereof, and composition containing peptide compound XDCEXPLORER (SHANGHAI) CO., LTD. (CN) 2022-08-30 — — US disclosed
US-20220213142-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2022-07-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11427615-B2 Peptide compound and application thereof, and composition containing peptide compound KISS1R, VIP, NPY1R KISS1R 1/4885ECE1 728/4885GHSR 56/4885
US-20220213142-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND KISS1R, VIP, SSTR3 KISS1R 1/4885ECE1 996/4885GHSR 35/4885
US-11807660-B2 Peptide compound and application thereof, and composition containing peptide compound KISS1R, VIP, SSTR3 KISS1R 1/4885ECE1 996/4885GHSR 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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