Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 16/20 | 0.62 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.59 |
| ▸ | ECE1 | P42892 | 1/20 | 0.57 |
| ▸ | GHSR | Q92847 | 1/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | NPY4R | P50391 | 1/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29657355 | 0.93 | KISS1R (0.61) | KISS1RECE1GHSR | |
| SCHEMBL10168837 | 0.91 | ECE1 (0.62) | KISS1RECE1 | |
| SCHEMBL14685610 | 0.91 | KISS1R (0.62) | KISS1RNPBWR1ECE1 | |
| SCHEMBL30464865 | 0.89 | NPY4R (0.61) | KISS1RECE1NPY1RNPY2RNPY4R | |
| SCHEMBL29825066 | 0.89 | NPY4R (0.61) | KISS1RNPBWR1GHSRNPY1RNPY2R | |
| Glycine SCHEMBL3497691 | 0.89 | KISS1R (0.58) | KISS1RECE1 | |
| SCHEMBL29816038 | 0.88 | ERAP2 (0.58) | KISS1RNPBWR1 | |
| SCHEMBL31078370 | 0.88 | NPBWR1 (0.57) | KISS1RNPBWR1 | |
| SCHEMBL30436748 | 0.88 | KISS1R (0.60) | KISS1RECE1NPY1RNPY2RNPY4R | |
| SCHEMBL30464857 | 0.88 | NPY4R (0.61) | KISS1RECE1NPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160241-A1 | NOVEL COMPOUND HAVING GPR54 AGONISTIC ACTIVITY | KYOTO UNIVERSITY (JP) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160241-A1 | NOVEL COMPOUND HAVING GPR54 AGONISTIC ACTIVITY | GPR52, GPR84, GPR4 | KISS1R 160/4885NPBWR1 222/4885ECE1 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.