Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | EPOR | P19235 | 7/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16620624 | 0.82 | TAAR1 (0.57) | EPHX2EPORLMNATSHRHDAC3 | |
| SCHEMBL29025356 | 0.77 | EPHX2 (0.57) | EPHX2MMP3MMP8MMP9LMNA | |
| SCHEMBL15894527 | 0.76 | LMNA (0.53) | EPHX2LMNATSHRHDAC3HDAC1 | |
| SCHEMBL8099440 | 0.76 | HDAC3 (0.57) | EPHX2MMP3MMP8MMP9LMNA | |
| SCHEMBL21069431 | 0.74 | EPHX2 (0.61) | EPHX2EPORMMP3MMP8MMP9 | |
| SCHEMBL21071040 | 0.74 | EPHX2 (0.61) | EPHX2EPORMMP3MMP8MMP9 | |
| SCHEMBL17117375 | 0.73 | TAAR1 (0.72) | LMNATSHRHDAC3HDAC1HDAC2 | |
| SCHEMBL17390846 | 0.73 | EPHX2 (0.59) | EPHX2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL3288103 | 0.73 | TLR2 (0.54) | EPHX2EPORSIRT2MMP3MMP8 | |
| SCHEMBL9932903 | 0.72 | SIRT2 (0.59) | EPHX2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3972984-A1 | PROCESS FOR THE PREPARATION OF GALNAC PHOSPHORAMIDITE EPIMERS | F. Hoffmann-La Roche AG (CH) | 2022-03-30 | — | — | EP | disclosed |