Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2975201 | 0.87 | CYP1A2 (0.37) | CYP1A2CYP3A4HSD17B10CYP2D6CYP2C9 | |
| SCHEMBL617020 | 0.87 | CYP1A2 (0.37) | CYP1A2CYP3A4HSD17B10CYP2D6CYP2C9 | |
| SCHEMBL2973834 | 0.83 | CYP1A2 (0.39) | CYP1A2CYP3A4HSD17B10CYP2D6CYP2C9 | |
| SCHEMBL3058003 | 0.81 | CYP1A2 (0.37) | CYP1A2CYP3A4HSD17B10CYP2D6CYP2C9 | |
| SCHEMBL2957703 | 0.81 | CYP1A2 (0.37) | CYP1A2CYP3A4HSD17B10CYP2D6CYP2C9 | |
| SCHEMBL18242620 | 0.74 | ALDH1A1 (0.40) | CYP1A2CYP3A4CYP2C9ALDH1A1MAPT | |
| SCHEMBL216980 | 0.74 | ALDH1A1 (0.40) | CYP1A2CYP3A4HSD17B10CYP2D6CYP2C9 | |
| SCHEMBL2478927 | 0.74 | RAB9A (0.40) | CYP1A2CYP3A4HSD17B10CYP2D6CYP2C9 | |
| SCHEMBL2960382 | 0.73 | ALDH1A1 (0.37) | CYP1A2CYP3A4HSD17B10CYP2D6CYP2C9 | |
| SCHEMBL4719922 | 0.73 | MALT1 (0.35) | CYP1A2CYP3A4HSD17B10CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763562-B2 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | AP2M1, AP1M1, PYM1 | CYP1A2 2409/4885CYP3A4 1385/4885HSD17B10 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.