Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.49 |
| ▸ | NPY1R | P25929 | 2/20 | 0.49 |
| ▸ | NPY4R | P50391 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30804496 | 0.89 | FOLH1 (0.60) | OPRD1OPRM1OPRK1NPY1RNPY4R | |
| SCHEMBL31257018 | 0.89 | OPRD1 (0.60) | OPRD1OPRM1OPRK1 | |
| SCHEMBL31332087 | 0.87 | OPRD1 (0.68) | OPRD1OPRM1OPRK1CTSB | |
| SCHEMBL4257186 | 0.85 | OPRD1 (0.50) | OPRD1OPRM1OPRK1 | |
| SCHEMBL4257177 | 0.85 | OPRD1 (0.50) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29350940 | 0.82 | OPRD1 (0.55) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29904057 | 0.82 | OPRD1 (0.66) | OPRD1OPRM1OPRK1 | |
| SCHEMBL31614444 | 0.82 | OPRD1 (0.56) | OPRD1OPRM1OPRK1NPY5RNPY1R | |
| SCHEMBL30440289 | 0.82 | OPRD1 (0.56) | OPRD1OPRM1OPRK1 | |
| SCHEMBL10520794 | 0.81 | FOLH1 (0.67) | OPRD1OPRM1NPY5RNPY1RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114480534-B | Protein semisynthesis by chemoenzymatic methods based on transpeptidase | 清华大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-114480534-A | Protein semi-synthesis based on chemical enzymatic methods of transpeptidase | 清华大学 | 2022-05-13 | — | — | CN | disclosed |