Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
| ▸ | NPY4R | P50391 | 1/20 | 0.53 |
| ▸ | IL1RN | P18510 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520794 | 0.92 | FOLH1 (0.67) | FOLH1OPRD1OPRM1ACENPY1R | |
| SCHEMBL29658002 | 0.89 | OPRD1 (0.56) | OPRD1OPRM1CTSBNPY1RNPY4R | |
| SCHEMBL31257018 | 0.89 | OPRD1 (0.60) | FOLH1OPRD1OPRM1OPRK1 | |
| SCHEMBL9332741 | 0.89 | ACE (0.54) | FOLH1OPRD1OPRM1ACEOPRK1 | |
| SCHEMBL9332730 | 0.89 | ACE (0.54) | FOLH1OPRD1OPRM1ACEOPRK1 | |
| SCHEMBL29789592 | 0.88 | CTSB (0.64) | OPRD1OPRM1CTSBACEOPRK1 | |
| SCHEMBL30396564 | 0.88 | ACE (0.63) | FOLH1OPRD1OPRM1CTSBACE | |
| SCHEMBL29993603 | 0.87 | ACE (0.53) | FOLH1OPRD1OPRM1ACEOPRK1 | |
| SCHEMBL31256940 | 0.87 | OPRD1 (0.69) | OPRD1OPRM1NPY1RNPY2RNPY4R | |
| SCHEMBL29994216 | 0.87 | OPRD1 (0.58) | FOLH1OPRD1OPRM1CTSBACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117462693-A | XTEN conjugate compositions and methods of making the same | 阿穆尼克斯运营公司 | 2024-01-30 | — | — | CN | disclosed |