SCHEMBL2965948

SCHEMBL2965948

FC(F)(F)C1=CCc2cc(Br)ccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 1/20 0.38
SRD5A2 P31213 1/20 0.38
PNMT P11086 2/20 0.37
ADRA2A P08913 1/20 0.37
S100A4 P26447 1/20 0.36
METAP1 P53582 1/20 0.36
TDP2 O95551 1/20 0.35
PARP10 Q53GL7 1/20 0.35
PARP11 Q9NR21 1/20 0.35
KDM1A O60341 2/20 0.33
PDK2 Q15119 1/20 0.33
PTPRC P08575 1/20 0.32
ABHD6 Q9BV23 1/20 0.31
CYP19A1 P11511 2/20 0.31
CYP11B1 P15538 2/20 0.31
CYP11B2 P19099 2/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2974933 0.85 PNMT (0.37) PNMTADRA2AS100A4METAP1TDP2
SCHEMBL2968043 0.75 METAP1 (0.39) SRD5A1SRD5A2PNMTADRA2AS100A4
SCHEMBL7139823 0.74 MPO (0.43) METAP1PDK2
SCHEMBL2963487 0.71 METAP1 (0.39) SRD5A1SRD5A2PNMTADRA2AS100A4
SCHEMBL18769959 0.71 METAP1 (0.39) SRD5A1SRD5A2PNMTADRA2AS100A4
SCHEMBL1530559 0.71 METAP1 (0.35) SRD5A1SRD5A2S100A4METAP1TDP2
SCHEMBL2963071 0.70 SRD5A1 (0.38) SRD5A1SRD5A2PNMTADRA2AS100A4
SCHEMBL2963361 0.67 CYP3A4 (0.42) SRD5A1SRD5A2METAP1TDP2PARP10
SCHEMBL17362233 0.67 METAP1 (0.36) SRD5A1SRD5A2PNMTADRA2AMETAP1
SCHEMBL2975322 0.67 METAP1 (0.36) SRD5A1SRD5A2PNMTADRA2AS100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 SRD5A1 3106/4885SRD5A2 2775/4885PNMT 2021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.