Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 6/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.46 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 5/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547180 | 1.00 | SRC (0.54) | SRCFLT3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20547441 | 0.97 | SRC (0.53) | SRCFLT3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30675136 | 0.89 | SMN1; SMN2 (0.51) | FLT3NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL20547610 | 0.89 | NPC1 (0.52) | FLT3NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL29659648 | 0.89 | NPC1 (0.52) | FLT3NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL20547188 | 0.88 | YTHDC1 (0.55) | FLT3NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL29659534 | 0.88 | YTHDC1 (0.55) | FLT3NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL20547186 | 0.86 | NPC1 (0.52) | FLT3NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL29659624 | 0.86 | NPC1 (0.52) | FLT3NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL20547474 | 0.86 | FLT3 (0.49) | FLT3NPC1RAB9ASMN1; SMN2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615535-B1 | 9-(2-OXACYCLOALKYL)-9H-PURINE-2,6-DIAMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF SKIN DISORDERS | UNIV PALACKEHO (CZ) | 2022-06-15 | — | — | EP | disclosed |