Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 4/20 | 0.51 |
| ▸ | CDK2 | P24941 | 6/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 6/20 | 0.46 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547610 | 0.89 | NPC1 (0.52) | SMN1; SMN2NPC1RAB9AFLT3CDK2 | |
| SCHEMBL29659648 | 0.89 | NPC1 (0.52) | SMN1; SMN2NPC1RAB9AFLT3CDK2 | |
| SCHEMBL29659565 | 0.89 | SRC (0.54) | SMN1; SMN2NPC1RAB9AFLT3CDK2 | |
| SCHEMBL20547180 | 0.89 | SRC (0.54) | SMN1; SMN2NPC1RAB9AFLT3CDK2 | |
| SCHEMBL29659534 | 0.88 | YTHDC1 (0.55) | SMN1; SMN2NPC1RAB9AFLT3CDK2 | |
| SCHEMBL20547188 | 0.88 | YTHDC1 (0.55) | SMN1; SMN2NPC1RAB9AFLT3CDK2 | |
| SCHEMBL20547474 | 0.86 | FLT3 (0.49) | SMN1; SMN2NPC1RAB9AFLT3CDK2 | |
| SCHEMBL20547441 | 0.86 | SRC (0.53) | SMN1; SMN2NPC1RAB9AFLT3CDK2 | |
| SCHEMBL20547532 | 0.85 | YTHDC1 (0.51) | SMN1; SMN2NPC1RAB9AFLT3CDK2 | |
| SCHEMBL29659620 | 0.85 | YTHDC1 (0.51) | SMN1; SMN2NPC1RAB9AFLT3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532498-A1 | HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND THERAPY OF CIRCADIAN RHYTHM DISORDERS | Univerzita Palackého v Olomouci (CZ) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023232171-A1 | HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND THERAPY OF CIRCADIAN RHYTHM DISORDERS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2023-12-07 | — | — | WO | disclosed |