Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22102558 | 1.00 | L3MBTL1 (0.47) | L3MBTL1KDM4EPOLBCTDSP1TDP1 | |
| SCHEMBL22102561 | 0.85 | CA12 (0.50) | L3MBTL1KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL29660431 | 0.85 | CA12 (0.50) | L3MBTL1KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL7270589 | 0.82 | CA12 (0.50) | L3MBTL1POLBTDP1KMT2AMEN1 | |
| SCHEMBL7675302 | 0.81 | MEN1 (0.41) | KDM4EFLT3KMT2AMEN1RECQL | |
| SCHEMBL11722874 | 0.81 | MAPT (0.49) | KDM4EPOLBTDP1KMT2AMEN1 | |
| SCHEMBL13091618 | 0.80 | POLB (0.41) | KDM4EPOLBFLT3KMT2AMEN1 | |
| SCHEMBL7270717 | 0.79 | MAPT (0.46) | L3MBTL1KDM4EPOLBTDP1KMT2A | |
| SCHEMBL28643739 | 0.78 | ALDH1A1 (0.40) | KDM4ETDP1FLT3KMT2AMEN1 | |
| SCHEMBL5810242 | 0.76 | FLT3 (0.41) | KDM4EPOLBFLT3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195492-B | Novel compound with three-fused ring structure, preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2022-07-08 | — | — | CN | disclosed |