Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | CLK1 | P49759 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.52 |
| ▸ | CDC25A | P30304 | 2/20 | 0.51 |
| ▸ | CDC25B | P30305 | 2/20 | 0.51 |
| ▸ | CDC25C | P30307 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29660343 | 0.91 | RAB9A (0.63) | RAB9AGAAMAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL201788 | 0.89 | RAB9A (0.67) | RAB9AGAAMAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL27108642 | 0.89 | RAB9A (0.61) | RAB9AGAAMAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL29660348 | 0.89 | RAB9A (0.62) | RAB9AGAAMAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL22939614 | 0.88 | RAB9A (0.53) | RAB9AGAAMAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL29660390 | 0.88 | RAB9A (0.54) | RAB9AGAAMAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL29911241 | 0.88 | RAB9A (0.54) | RAB9AGAAMAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL29660304 | 0.88 | RAB9A (0.54) | RAB9AGAAMAPTHSP90AA1SMN1; SMN2 | |
| SCHEMBL22939882 | 0.88 | MMP13 (0.62) | RAB9AGAAMAPTHSP90AA1NPC1 | |
| SCHEMBL12582252 | 0.87 | RAB9A (0.72) | RAB9AGAAMAPTHSP90AA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003955-A1 | INHIBITORS OF HUMAN ATGL | Karl-Franzens-Universität Graz (AT) | 2022-06-01 | — | — | EP | disclosed |