SCHEMBL29660486

SCHEMBL29660486

CC(C)[Si](C(C)C)(C(C)C)n1ccc2c(F)ccnc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1002153 1.00
SCHEMBL15280118 0.81 CCR1 (0.38)
SCHEMBL306515 0.80 ENPP3 (0.36)
SCHEMBL2794776 0.80
SCHEMBL29660466 0.80 MGAM (0.34)
SCHEMBL794853 0.80 MGAM (0.34)
SCHEMBL29378331 0.80 ENPP3 (0.36)
SCHEMBL2114148 0.80 AR (0.33)
SCHEMBL29660452 0.79
SCHEMBL15155025 0.79 MGAM (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626886-A1 JAK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS OnQuality Pharmaceuticals China Ltd. (CN) 2025-10-08 EP disclosed
EP-4247812-A1 SUBSTITUTED PYRROLO [2, 3-B] PYRIDINE AND PYRAZOLO [3, 4-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS Fochon Biosciences, Ltd. (CN) 2023-09-27 EP disclosed
CN-116568686-A Substituted pyrrolo [2,3-b ] pyridine and pyrazolo [3,4-b ] pyridine derivatives as protein kinase inhibitors 重庆复尚源创医药技术有限公司 2023-08-08 CN disclosed
CN-114746090-A Azaindole carboxamide compounds for the treatment of mycobacterial infections 结核病药物开发全球联盟公司 2022-07-12 CN disclosed
WO-2022105746-A1 SUBSTITUTED PYRROLO [2, 3-b] PYRIDINE AND PYRAZOLO [3, 4-b] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS FOCHON PHARMACEUTICALS, LTD. (CN) 2022-05-27 WO disclosed