Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.50 |
| ▸ | SKP1 | P63208 | 1/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20507503 | 1.00 | CKS1B (0.50) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL30982158 | 0.95 | MAPT (0.52) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL20507562 | 0.95 | MAPT (0.52) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL5237966 | 0.83 | MAPT (0.57) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL1990159 | 0.82 | CKS1B (0.53) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL30316131 | 0.82 | CKS1B (0.53) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL28735924 | 0.82 | MAPT (0.58) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL15584576 | 0.82 | GPR119 (0.56) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL29660540 | 0.82 | GPR119 (0.56) | CKS1BSKP1SKP2MAPTALDH1A1 | |
| SCHEMBL3613205 | 0.82 | MAPT (0.57) | CKS1BSKP1SKP2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013743-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | Nuvation Bio Inc. (US) | 2022-06-22 | — | — | EP | disclosed |
| CN-114502536-A | Heterocyclic compounds as kinase inhibitors | 诺维逊生物股份有限公司 | 2022-05-13 | — | — | CN | disclosed |