Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.49 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20507562 | 1.00 | MAPT (0.52) | MAPTALDH1A1LMNAMAP4K4PIK3CA | |
| SCHEMBL20507503 | 0.95 | CKS1B (0.50) | MAPTALDH1A1LMNAMAP4K4PIK3CA | |
| SCHEMBL29660548 | 0.95 | CKS1B (0.50) | MAPTALDH1A1LMNAMAP4K4PIK3CA | |
| SCHEMBL10320809 | 0.86 | WNT3A (0.56) | MAPTALDH1A1LMNAPDK2MEN1 | |
| SCHEMBL194454 | 0.86 | MAPT (0.53) | MAPTALDH1A1LMNAPIK3CASMARCA2 | |
| SCHEMBL12781530 | 0.85 | MAPT (0.52) | MAPTALDH1A1LMNAPIK3CAPDK2 | |
| SCHEMBL1432796 | 0.85 | POLB (0.53) | MAPTALDH1A1LMNAPDK2MEN1 | |
| SCHEMBL21464385 | 0.84 | ACHE (0.50) | MAPTALDH1A1LMNAMAP4K4PIK3CA | |
| SCHEMBL21594570 | 0.84 | MAPT (0.51) | MAPTALDH1A1LMNAPDK2MEN1 | |
| SCHEMBL21594569 | 0.84 | MAPT (0.51) | MAPTALDH1A1LMNAPIK3CAPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025108406-A1 | HETEROCYCLIC COMPOUND OF BIFUNCTIONAL CHIMERA FOR TARGETED DEGRADATION OF ANDROGEN RECEPTOR, AND USE THEREOF | 广东东阳光药业股份有限公司 | 2025-05-30 | — | — | WO | disclosed |
| CN-120025333-A | Heterocyclic compound of bifunctional chimera for targeting and degrading androgen receptor and application thereof | 广东东阳光药业股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| WO-2024123968-A1 | RNA TARGETING COMPOUNDS AND USES THEREOF | RANAR THERAPEUTICS, INC. (US) | 2024-06-13 | — | — | WO | disclosed |