Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22918085 | 1.00 | KDM1A (0.43) | KDM1AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22918092 | 0.82 | ELANE (0.47) | KDM1APTGER1RAB9ASMN1; SMN2 | |
| SCHEMBL29661076 | 0.82 | KDM1A (0.46) | KDM1AMAPK1PTGER1RAB9ASMN1; SMN2 | |
| SCHEMBL22918273 | 0.82 | KDM1A (0.46) | KDM1AMAPK1PTGER1RAB9ASMN1; SMN2 | |
| SCHEMBL20521874 | 0.79 | KDM1A (0.48) | KDM1AMAPK1PTGER1RAB9ASMN1; SMN2 | |
| SCHEMBL30221893 | 0.79 | KDM1A (0.48) | KDM1AMAPK1PTGER1RAB9ASMN1; SMN2 | |
| SCHEMBL31482951 | 0.79 | L3MBTL1 (0.48) | MEN1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1668610 | 0.79 | CCR5 (0.58) | CYP1A2PTGER1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22357315 | 0.79 | L3MBTL1 (0.48) | MEN1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28104163 | 0.79 | FFAR1 (0.45) | KDM1AMEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114616226-B | Pyridine derivatives as TMEM16A modulators for the treatment of respiratory disorders | TMEM16A有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-114616226-A | Pyridine derivatives as TMEM16A modulators for the treatment of respiratory disorders | TMEM16A有限公司 | 2022-06-10 | — | — | CN | disclosed |
| EP-4003516-A1 | PYRIDINE DERIVATIVES AS TMEM16A MODULATORS FOR USE IN THE TREATMENT OF RESPIRATORY CONDITIONS | TMEM16A LIMITED (GB) | 2022-06-01 | — | — | EP | disclosed |