Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23522048 | 1.00 | RAB9A (0.42) | RAB9AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL23522045 | 1.00 | RAB9A (0.42) | RAB9AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL23522145 | 0.86 | KDM4E (0.51) | RAB9AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL30418860 | 0.86 | KDM4E (0.51) | RAB9AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL23522147 | 0.86 | KDM4E (0.51) | RAB9AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL23522223 | 0.86 | ALDH1A1 (0.43) | RAB9AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL23522224 | 0.86 | ALDH1A1 (0.43) | RAB9AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL23521838 | 0.85 | KDM4E (0.45) | RAB9AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL23521842 | 0.85 | KDM4E (0.45) | RAB9AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL23521919 | 0.85 | KDM4E (0.45) | RAB9AKDM4EMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838898-B1 | ISOINDOLIN-1-ONE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AS AN EFFECTIVE COMPONENT FOR PREVENTING OR TREATING CANCER | KOREA RES INST CHEMICAL TECH (KR) | 2023-06-07 | — | — | EP | disclosed |
| EP-4005572-A1 | BENZAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | Korea Research Institute of Chemical Technology (KR) | 2022-06-01 | — | — | EP | disclosed |