SCHEMBL29662242

C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)[C@@H](C)O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	7/20	0.55

▸	CALCR	P30988	7/20	0.55

▸	OPRM1	P35372	4/20	0.55

▸	OPRK1	P41145	4/20	0.55

▸	OPRD1	P41143	2/20	0.55

▸	KEAP1	Q14145	1/20	0.55

▸	CXCR4	P61073	1/20	0.54

▸	CALCRL	Q16602	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29662379	0.96	KEAP1 (0.56)	RAMP3CALCROPRM1OPRD1KEAP1
SCHEMBL30712913	0.88	NPY2R (0.64)	OPRD1KEAP1
SCHEMBL29678305	0.87	IL23R (0.59)	RAMP3CALCROPRM1OPRD1KEAP1
SCHEMBL31730324	0.87	CXCR4 (0.60)	RAMP3CALCRCXCR4
SCHEMBL30085017	0.87	CXCR4 (0.60)	OPRM1OPRK1KEAP1CXCR4
SCHEMBL29678292	0.87	KEAP1 (0.58)	OPRM1OPRD1KEAP1
SCHEMBL29662252	0.87	C5AR1 (0.66)	RAMP3CALCRKEAP1CXCR4
SCHEMBL30262202	0.86	CXCR4 (0.59)	RAMP3CALCRCXCR4
SCHEMBL29496464	0.85	KEAP1 (0.59)	RAMP3CALCROPRM1OPRD1KEAP1
SCHEMBL31307292	0.85	CALCRL (0.56)	RAMP3CALCRKEAP1CALCRL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-112724238-B	Bioactive peptide with amino acid structure FREGTTPKPK, and preparation method and application thereof	浙江辉肽生命健康科技有限公司	2022-05-31	—	—	CN	claimed
CN-112724238-B	Bioactive peptide with amino acid structure FREGTTPKPK, and preparation method and application thereof	浙江辉肽生命健康科技有限公司	2022-05-31	—	—	CN	disclosed