SCHEMBL2966342

SCHEMBL2966342

CCCCc1ccccc1-c1cc2c(cc1Br)C(C)=CC2

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
LIPG Q9Y5X9 1/20 0.31
TLR8 Q9NR97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2959220 0.95 NR1H2 (0.32) NR1H2NR1H3LIPGTLR8
SCHEMBL2974752 0.79 NR1H2 (0.31) NR1H2NR1H3LIPG
SCHEMBL2975540 0.78 NR1H2 (0.32) NR1H2NR1H3LIPGTLR8
SCHEMBL2966345 0.78 SKP2 (0.37)
SCHEMBL2974247 0.78 ALDH1A1 (0.35)
SCHEMBL2973964 0.78 PPARA (0.31) NR1H2NR1H3
SCHEMBL2963033 0.77 ELANE (0.32) NR1H2NR1H3LIPG
SCHEMBL2971426 0.77 NR1H2 (0.32) NR1H2NR1H3LIPGTLR8
SCHEMBL2970869 0.77 NR1H2 (0.32) NR1H2NR1H3LIPG
SCHEMBL2975356 0.76 GPR3 (0.33) NR1H2NR1H3LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 NR1H2 1227/4885NR1H3 1012/4885LIPG 3839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.