SCHEMBL29664101

SCHEMBL29664101

COC1=C(c2ccc(OC)cc2)C(=O)C(=O)C(c2ccc(OC)cc2)=C1OC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ME2 P23368 1/20 0.62
ME1 P48163 1/20 0.62
ME3 Q16798 1/20 0.62
PDE4B Q07343 1/20 0.57
MAPT P10636 4/20 0.56
NPC1 O15118 1/20 0.56
TP53 P04637 1/20 0.56
TSHR P16473 1/20 0.56
RAB9A P51151 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
BACE1 P56817 2/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
FGFR1 P11362 1/20 0.50
SRC P12931 1/20 0.50
FGFR2 P21802 1/20 0.50
FGFR4 P22455 1/20 0.50
FGFR3 P22607 1/20 0.50
MITF O75030 1/20 0.50
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10424199 0.84 ME2 (0.69) ME2ME1ME3MAPTNPC1
SCHEMBL20299548 0.82 ME2 (0.67) ME2ME1ME3MAPTNPC1
SCHEMBL5164345 0.82 PDE4B (0.83) PDE4BMAPTNPC1TP53TSHR
SCHEMBL13141855 0.79 BACE1 (0.62) ME2ME1ME3PDE4BMAPT
SCHEMBL9723700 0.79 BACE1 (0.62) ME2ME1ME3PDE4BMAPT
SCHEMBL30320677 0.78 ME2 (0.57) ME2ME1ME3MAPTNPC1
SCHEMBL13585812 0.78 BACE1 (0.61) ME2ME1ME3PDE4BMAPT
SCHEMBL13569202 0.78 BACE1 (0.61) ME2ME1ME3PDE4BMAPT
SCHEMBL9274767 0.78 ME2 (0.52) ME2ME1ME3PDE4BMAPT
SCHEMBL1063908 0.75 ME2 (0.86) ME2ME1ME3PDE4BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220142907-A1 MYCELIUM BIOPOLYMERS FOR HEALTH AND BEAUTY APPLICATIONS ECOVATIVE LLC 2022-05-12 US disclosed