SCHEMBL29664170

SCHEMBL29664170

Cc1ccc2cc(OC#N)ccc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.54
CYP1A2 P05177 4/20 0.54
TDP1 Q9NUW8 1/20 0.46
NQO1 P15559 1/20 0.37
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
AR P10275 3/20 0.35
FLT3 P36888 1/20 0.35
ACHE P22303 1/20 0.34
ALDH1A1 P00352 3/20 0.34
NCK1 P16333 1/20 0.34
BACE1 P56817 1/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ESR1 P03372 1/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17042459 1.00 CYP2A6 (0.54) CYP2A6CYP1A2TDP1NQO1KMT2A
SCHEMBL185504 0.87 NQO1 (0.39) CYP2A6CYP1A2TDP1NQO1KMT2A
SCHEMBL184681 0.82 CYP1A2 (0.39) CYP2A6CYP1A2TDP1NQO1KMT2A
SCHEMBL6056041 0.82 NQO1 (0.37) CYP2A6CYP1A2TDP1NQO1KMT2A
SCHEMBL23607927 0.81 CYP2A6 (0.56) CYP2A6CYP1A2NQO1KMT2AMEN1
SCHEMBL764016 0.80 ACHE (0.48) CYP2A6TDP1KMT2AMEN1AR
SCHEMBL2496298 0.79 CYP2A6 (0.54) CYP2A6CYP1A2TDP1KMT2AMEN1
SCHEMBL8452517 0.78 CYP2A6 (0.52) CYP2A6CYP1A2TDP1KMT2AMEN1
SCHEMBL30003929 0.78 CYP2A6 (0.52) CYP2A6CYP1A2TDP1KMT2AMEN1
SCHEMBL17042486 0.78 CYP2A6 (0.57) CYP2A6CYP1A2NQO1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022124129-A1 RESIN COMPOSITION, PREPREG, RESIN SHEET, METAL FOIL-CLAD LAYERED BOARD, AND PRINTED WIRING BOARD 三菱瓦斯化学株式会社 2022-06-16 WO disclosed