Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28226097 | 0.80 | ESR1 (0.41) | MAP4K4ALDH1A1KDM4ERIPK2SRC | |
| SCHEMBL29664356 | 0.79 | MAP4K1 (0.35) | CYP11B1CYP11B2PIK3CDIRAK4 | |
| SCHEMBL1719817 | 0.78 | HTR2B (0.44) | ALDH1A1HSD17B10POLBKDM4ECYP11B1 | |
| SCHEMBL944155 | 0.76 | MAP3K5 (0.43) | ALDH1A1HPGDHSD17B10KDM4EMAOA | |
| SCHEMBL30853796 | 0.76 | MAP3K5 (0.43) | ALDH1A1HPGDHSD17B10KDM4EMAOA | |
| SCHEMBL29286631 | 0.75 | ADORA1 (0.41) | HPGDRIPK2 | |
| SCHEMBL28713147 | 0.75 | HPGD (0.43) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL3970148 | 0.74 | MAP4K4 (0.46) | MAP4K4ALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL27761911 | 0.73 | LMNA (0.43) | ALDH1A1HPGDKDM4ESRCMAPT | |
| SCHEMBL28695130 | 0.72 | ABL1 (0.51) | ALDH1A1HPGDKDM4ETNK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480543-B | 2,6, 8-polysubstituted imidazo [1,2-a ] pyrazine and synthetic method and application thereof | 无锡市第二人民医院 | 2022-05-17 | — | — | CN | disclosed |