Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.33 |
| ▸ | CD63 | P08962 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664258 | 0.79 | MAP4K4 (0.41) | CYP11B2CYP11B1IRAK4PIK3CD | |
| SCHEMBL28713216 | 0.75 | ALDH1A1 (0.34) | CYP11B2CYP11B1CYP19A1ADRA2BPIK3CD | |
| SCHEMBL20339238 | 0.73 | CYP11B2 (0.50) | CYP11B2CYP11B1 | |
| SCHEMBL28344931 | 0.71 | CYP11B2 (0.52) | CYP11B2CYP11B1 | |
| SCHEMBL14809682 | 0.68 | IRAK4 (0.39) | CYP11B2CYP11B1IRAK4 | |
| SCHEMBL23153759 | 0.66 | PDE4A (0.31) | — | |
| SCHEMBL20339309 | 0.65 | CYP11B1 (0.51) | CYP11B2CYP11B1CYP19A1ABL1 | |
| SCHEMBL18250727 | 0.63 | — | — | |
| SCHEMBL15315959 | 0.63 | LMNA (0.37) | — | |
| SCHEMBL28400995 | 0.62 | NPC1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480543-B | 2,6, 8-polysubstituted imidazo [1,2-a ] pyrazine and synthetic method and application thereof | 无锡市第二人民医院 | 2022-05-17 | — | — | CN | disclosed |