Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | HTR2C | P28335 | 3/20 | 0.57 |
| ▸ | HTR2B | P41595 | 3/20 | 0.57 |
| ▸ | HTR3A | P46098 | 2/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | FPR3 | P25089 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 1/20 | 0.56 |
| ▸ | HTR1E | P28566 | 1/20 | 0.56 |
| ▸ | GPR183 | P32249 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6100222 | 1.00 | HTR6 (0.58) | HTR6HTR2AHTR2CHTR2BHTR3A | |
| SCHEMBL905960 | 0.88 | HTR2C (0.70) | HTR6HTR2AHTR2CHTR2BHTR3A | |
| SCHEMBL6099835 | 0.86 | HTR2C (0.55) | HTR6HTR2AHTR2CHTR2BHTR3A | |
| SCHEMBL30138420 | 0.86 | HTR2C (0.55) | HTR6HTR2AHTR2CHTR2BHTR3A | |
| SCHEMBL3104344 | 0.86 | HTR2C (0.57) | HTR6HTR2AHTR2CHTR2BHTR3A | |
| Hydrochloric Acid SCHEMBL31061265 | 0.85 | HTR2C (0.58) | HTR6HTR2AHTR2CHTR2BHTR3A | |
| SCHEMBL6097970 | 0.80 | HTR2C (0.47) | HTR6HTR2AHTR2CHTR2BHTR3A | |
| SCHEMBL6100255 | 0.79 | HTR2C (0.53) | HTR6HTR2AHTR2CHTR2BHTR3A | |
| SCHEMBL3266629 | 0.79 | HTR3A (0.54) | HTR6HTR2AHTR2CHTR2BHTR3A | |
| SCHEMBL6097031 | 0.79 | HTR2C (0.53) | HTR6HTR2AHTR2CHTR2BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728939-B | GLP-1 receptor agonists and uses thereof | 日东制药株式会社 | 2023-12-08 | — | — | CN | disclosed |
| CN-114728939-A | GLP-1 receptor agonists and uses thereof | 日东制药株式会社 | 2022-07-08 | — | — | CN | disclosed |