Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664519 | 0.90 | GAA (0.43) | GAAHPGDSALKBH2HSD17B10DDB1 | |
| SCHEMBL29664287 | 0.88 | DRD2 (0.46) | GAAHPGDSALKBH2HSD17B10DDB1 | |
| SCHEMBL29664346 | 0.88 | HPGD (0.53) | GAAALDH1A1EGFRFGFR1KDR | |
| SCHEMBL29664147 | 0.84 | EGFR (0.52) | GAAALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL19358349 | 0.81 | GAA (0.53) | GAAHPGDSALKBH2DDB1CRBN | |
| SCHEMBL19248968 | 0.81 | GAA (0.53) | GAAHPGDSALKBH2DDB1CRBN | |
| SCHEMBL23719148 | 0.78 | MAPK10 (0.59) | GAAHPGDSALKBH2TSHREGFR | |
| SCHEMBL20438073 | 0.77 | GAA (0.49) | GAAHPGDSALKBH2HSD17B10DDB1 | |
| SCHEMBL22594371 | 0.77 | HPGDS (0.49) | GAAHPGDSALKBH2DDB1CRBN | |
| SCHEMBL3825768 | 0.77 | HPGDS (0.57) | GAAHPGDSALKBH2EGFRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728909-A | Composition for preventing or treating cancer comprising novel trifluoromethylphenylpyrazole derivative as active ingredient | 韩国原子力医学院 | 2022-07-08 | — | — | CN | disclosed |