Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | MELK | Q14680 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23144521 | 1.00 | MKNK1 (0.50) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL23144535 | 0.88 | MAOA (0.53) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL29664332 | 0.88 | MAOA (0.53) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL23144559 | 0.85 | MAOA (0.55) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL29664364 | 0.84 | GRM4 (0.47) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL29664194 | 0.84 | MAP4K4 (0.44) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL23144544 | 0.84 | GRM4 (0.47) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL23144576 | 0.84 | MAP4K4 (0.44) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL23144557 | 0.83 | NTRK1 (0.57) | MKNK1MKNK2MEN1PSIP1AXL | |
| SCHEMBL29664342 | 0.83 | NTRK1 (0.57) | MKNK1MKNK2MEN1PSIP1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728909-A | Composition for preventing or treating cancer comprising novel trifluoromethylphenylpyrazole derivative as active ingredient | 韩国原子力医学院 | 2022-07-08 | — | — | CN | disclosed |