Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664530 | 0.81 | LMNA (0.74) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL29664494 | 0.81 | NPC1 (0.48) | L3MBTL1 | |
| SCHEMBL12417226 | 0.78 | LMNA (0.62) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL30878815 | 0.77 | LMNA (0.60) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL27625364 | 0.76 | LMNA (0.66) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL23412472 | 0.76 | POLB (0.65) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL18548983 | 0.76 | POLB (0.65) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL1965227 | 0.76 | LMNA (0.59) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL15436046 | 0.76 | KMT2A (0.62) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL29846090 | 0.76 | POLB (0.65) | ALDH1A1HTTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022096679-A1 | PROTEIN-PROTEIN INTERACTION MODULATORS OF AURORA KINASE A AND THEIR USE IN THE PREVENTION AND/OR TREATMENT OF CANCER | EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) | 2022-05-12 | — | — | WO | disclosed |