Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | ULK1 | O75385 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560890 | 1.00 | ADORA2A (0.38) | ADORA2AADORA1SRCABCG2ADORA3 | |
| SCHEMBL2295626 | 0.83 | MBOAT4 (0.40) | ALDH1A1 | |
| SCHEMBL31168492 | 0.83 | MBOAT4 (0.40) | ALDH1A1 | |
| SCHEMBL14910677 | 0.74 | ABCG2 (0.37) | SRCABCG2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL31003337 | 0.74 | ABCG2 (0.37) | SRCABCG2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL30954618 | 0.74 | ABCG2 (0.37) | ADORA2AADORA1SRCABCG2ADORA3 | |
| SCHEMBL25161730 | 0.69 | OGA (0.36) | ABCG2ALDH1A1CYP3A4TAAR1OGA | |
| SCHEMBL10267209 | 0.69 | OGA (0.35) | ABCG2ALDH1A1CYP3A4OGAHSD17B10 | |
| SCHEMBL10291128 | 0.69 | EDNRB (0.38) | ADORA1ABCG2ADORA3ALDH1A1TAAR1 | |
| SCHEMBL31003117 | 0.67 | ALDH1A1 (0.40) | ADORA2AADORA1ADORA3ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626864-A1 | LINEAR HETEROARYL DIAMIDE IRE1/XBP1S ACTIVATORS | Protego Biopharma, Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2025106949-A1 | WRN INHIBITORS | RADD PHARMACEUTICALS, INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| WO-2024118801-A1 | LINEAR HETEROARYL DIAMIDE IRE1/XBP1S ACTIVATORS | PROTEGO BIOPHARMA, INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| WO-2022121805-A1 | FUSED RING COMPOUND AS NAV1.8 INHIBITOR AND USE THEREOF | 成都康弘药业集团股份有限公司 | 2022-06-16 | — | — | WO | disclosed |