Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14507455 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL36866 | 0.93 | POLB (0.41) | ALDH1A1TSHRPOLBGAANPSR1 | |
| SCHEMBL18286498 | 0.92 | TSHR (0.40) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL17461770 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL12238135 | 0.90 | POLB (0.33) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL3842975 | 0.90 | ALDH1A1 (0.36) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL12533107 | 0.88 | POLB (0.33) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL14192095 | 0.88 | TSHR (0.42) | ALDH1A1TSHRCYP4F2CYP4A11THRB | |
| Ethylene Glycol SCHEMBL830063 | 0.86 | POLB (0.38) | POLBGAANPSR1CYP4F2CYP4A11 | |
| SCHEMBL19393389 | 0.86 | POLB (0.50) | ALDH1A1POLBGAANPSR1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4259689-A1 | NOVEL POLYMERS AND USES THEREOF | F. Hoffmann-La Roche AG (CH) | 2023-10-18 | — | — | EP | disclosed |
| CN-116601211-A | Novel polymers and their use | 豪夫迈·罗氏有限公司 | 2023-08-15 | — | — | CN | disclosed |
| WO-2022122937-A1 | NOVEL POLYMERS AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2022-06-16 | — | — | WO | disclosed |