Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36866 | 0.93 | POLB (0.41) | POLBGAANPSR1CHRM2CHRM4 | |
| SCHEMBL1198114 | 0.91 | TSHR (0.38) | POLBGAANPSR1CYP4F2CYP4A11 | |
| Bromide SCHEMBL16048766 | 0.88 | POLB (0.37) | POLBGAANPSR1CYP4F2CYP4A11 | |
| SCHEMBL106426 | 0.86 | CYP4F2 (0.40) | POLBGAANPSR1CYP4F2CYP4A11 | |
| SCHEMBL5308880 | 0.86 | POLB (0.36) | POLBGAANPSR1CYP4F2CYP4A11 | |
| SCHEMBL29664486 | 0.86 | ALDH1A1 (0.38) | POLBGAANPSR1CYP4F2CYP4A11 | |
| SCHEMBL19393389 | 0.86 | POLB (0.50) | POLBGAANPSR1CYP4F2CYP4A11 | |
| SCHEMBL14507455 | 0.86 | ALDH1A1 (0.38) | POLBGAANPSR1CYP4F2CYP4A11 | |
| SCHEMBL6661533 | 0.85 | CYP4F2 (0.46) | POLBGAANPSR1CYP4F2CYP4A11 | |
| SCHEMBL23153213 | 0.84 | ALDH1A1 (0.46) | POLBGAANPSR1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140206823-A1 | METHOD FOR REDUCING THE HALOGEN CONTENT OF A POLYMER | EVONIK OIL ADDITIVES GMBH (DE) | 2014-07-24 | — | — | US | disclosed |
| US-8143354-B2 | Process for preparing acid-terminated ATRP products | EVONIK RÖHM GMBH (DE) | 2012-03-27 | — | — | US | disclosed |
| US-20090326163-A1 | PROCESS FOR PREPARING ACID-TERMINATED ATRP PRODUCTS | EVONIK ROEHM GMBH (DE) | 2009-12-31 | — | — | US | disclosed |
| US-20090312498-A1 | PROCESS FOR PREPARING HYDROXY-TELECHELIC ATRP PRODUCTS | EVONIK ROEHM GMBH (DE) | 2009-12-17 | — | — | US | disclosed |
| US-20090275707-A1 | PROCESS FOR PREPARING HALOGEN-FREE ATRP PRODUCTS | EVONIK ROEHM GMBH (DE) | 2009-11-05 | — | — | US | disclosed |