Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.61 |
| ▸ | LOX | P28300 | 3/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23215147 | 1.00 | LOXL2 (0.61) | LOXL2LOXFFAR1PIK3CDPIK3CA | |
| SCHEMBL3445901 | 0.77 | RECQL (0.42) | LOXL2LOXPIK3CDPIK3CAPIK3CB | |
| SCHEMBL805488 | 0.77 | LOXL2 (0.69) | LOXL2LOXFFAR1PIK3CAACACB | |
| SCHEMBL178404 | 0.76 | LOXL2 (0.62) | LOXL2LOXFFAR1PDE5AACACB | |
| SCHEMBL130180 | 0.76 | LOXL2 (0.67) | LOXL2LOXFFAR1AAK1ACACB | |
| SCHEMBL449200 | 0.76 | LOXL2 (1.00) | LOXL2LOX | |
| SCHEMBL29841095 | 0.76 | GRM5 (0.46) | FFAR1AAK1CYP3A4DYRK1AENPP2 | |
| SCHEMBL2224895 | 0.76 | LOXL2 (0.67) | LOXL2LOXFFAR1ACACBDYRK1A | |
| SCHEMBL2092744 | 0.76 | LOXL2 (0.67) | LOXL2LOXFFAR1ACACBDYRK1A | |
| SCHEMBL17752 | 0.76 | LOXL2 (0.67) | LOXL2LOXFFAR1PDE5AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729044-A | Muscarinic acetylcholine M1Receptor antagonists | 帕珀莱恩医疗公司 | 2022-07-08 | — | — | CN | disclosed |