SCHEMBL17752

SCHEMBL17752

COc1cc(CO)ccn1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 4/20 0.67
LOX P28300 2/20 0.67
RECQL P46063 1/20 0.52
FFAR1 O14842 1/20 0.42
CBFB Q13951 2/20 0.40
GRM2 Q14416 1/20 0.40
KCNK3 O14649 1/20 0.39
KCNK9 Q9NPC2 1/20 0.39
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
PDE5A O76074 1/20 0.38
SLC13A5 Q86YT5 1/20 0.38
ACACB O00763 1/20 0.38
CDK2 P24941 2/20 0.38
CDK4 P11802 1/20 0.38
CCND1 P24385 1/20 0.38
MAOA P21397 1/20 0.37
DYRK1A Q13627 1/20 0.37
GSK3B P49841 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29841247 1.00 LOXL2 (0.67) LOXL2LOXRECQLFFAR1CBFB
SCHEMBL2497237 0.85 LOXL2 (0.62) LOXL2LOXRECQLFFAR1GRM2
SCHEMBL2940362 0.82 RECQL (0.50) LOXL2LOXRECQLNPC1POLB
SCHEMBL10183827 0.82 LOXL2 (0.46) LOXL2LOXRECQLCBFBNPC1
SCHEMBL14861189 0.82 LOX (0.59) LOXL2LOXFFAR1GRM2SLC13A5
SCHEMBL805488 0.82 LOXL2 (0.69) LOXL2LOXFFAR1SLC13A5ACACB
SCHEMBL8263374 0.80 LOXL2 (0.45) LOXL2LOXRECQLCBFBNPC1
SCHEMBL28980427 0.80 PDE2A (0.47) LOXL2LOXRECQLFFAR1CBFB
SCHEMBL2092744 0.80 LOXL2 (0.67) LOXL2LOXFFAR1SLC13A5ACACB
SCHEMBL449200 0.80 LOXL2 (1.00) LOXL2LOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138987-A1 MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS CONTINEUM THERAPEUTICS INC (US) 2026-05-21 US disclosed
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 US disclosed
US-12565501-B2 Muscarinic acetylcholine M1 receptor antagonists CONTINEUM THERAPEUTICS, INC. (US) 2026-03-03 US disclosed
US-20260028365-A1 TYROSINE KINASE 2 INHIBITORS AND USES THEREOF BIOGEN MA INC (US) 2026-01-29 US disclosed
US-12534463-B2 Substituted tricyclic compounds as FGFR inhibitors INCYTE CORPORATION (US) 2026-01-27 US disclosed
US-12421224-B2 Azetidinyl O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranosidase inhibitors BIOGEN MA INC. (US) 2025-09-23 US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 US disclosed
CN-112334466-B Compounds of formula (I) CTXT私人有限公司 2025-05-30 CN disclosed
US-20250171455-A1 MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS CONTINEUM THERAPEUTICS INC (US) 2025-05-29 US disclosed
US-20250122182-A1 MYST Inhibitors Isosterix, Inc. 2025-04-17 US disclosed
US-6071921-A Chemical compounds ZENECA LIMITED (GB) 2000-06-06 US disclosed
US-5962458-A ANGIOGENESIS INHIBITORS, ANTICANCER AGENTS, ANTIDIABETIC AGENTS, SKIN DISORDERS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, VISION DEFECTS ZENECA LIMITED (GB) 1999-10-05 US disclosed
CN-1205694-A Quinazoline derivatives ZENECA LTD (GB) 1999-01-20 CN disclosed
EP-0873319-A1 QUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1998-10-28 EP disclosed
US-5776983-A ANTIDIABETIC AGENTS, OBESITY, GASTROINTESTINAL DISORDERS BRISTOL-MYERS SQUIBB COMPANY (US) 1998-07-07 US disclosed
WO-1997022596-A1 QUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1997-06-26 WO disclosed
CN-1109050-A Catecholamine surrogates useful as beta3 agonists BRISTOL MYERS SQUIBB CO (US) 1995-09-27 CN disclosed
EP-0659737-A2 Catecholamine surrogates useful as B3 agonists BRISTOL-MYERS SQUIBB COMPANY (US) 1995-06-28 EP disclosed
EP-0244728-B1 USE OF HETEROARYLETHYL AMINES TO STIMULATE ANIMAL GROWTH, HETEROARYLETHYL AMINES AND PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1992-11-11 EP disclosed
EP-0244728-A2 Use of heteroarylethyl amines to stimulate animal growth, heteroarylethyl amines and process for their preparation BAYER AG (DE) 1987-11-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534463-B2 Substituted tricyclic compounds as FGFR inhibitors FGFR3, FGFR1, FGFR4 LOXL2 180/4885LOX 354/4885RECQL 1490/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B LOXL2 3529/4885LOX 3086/4885RECQL 3719/4885
US-12421224-B2 Azetidinyl O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranosidase inhibitors UGGT1, MAN2A1, MAN2B2 LOXL2 1738/4885LOX 868/4885RECQL 1522/4885
US-12565501-B2 Muscarinic acetylcholine M1 receptor antagonists CHRM1, CHRM2, CHRM3 LOXL2 2718/4885LOX 1263/4885RECQL 1198/4885
US-20250122182-A1 MYST Inhibitors MNAT1, SUGT1, ACAT2 LOXL2 1775/4885LOX 2307/4885RECQL 1282/4885
US-20260138987-A1 MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS CHRM1, CHRM5, CHRM3 LOXL2 2837/4885LOX 1208/4885RECQL 1278/4885
US-20250171455-A1 MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS CHRM1, CHRM2, CHRM3 LOXL2 2285/4885LOX 1331/4885RECQL 1871/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 LOXL2 3721/4885LOX 3242/4885RECQL 3738/4885
US-20260028365-A1 TYROSINE KINASE 2 INHIBITORS AND USES THEREOF TYK2, ERBB2, ROS1 LOXL2 714/4885LOX 572/4885RECQL 3335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.