Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410040 | 0.96 | LOXL2 (0.55) | LOXL2CYP2A6RORCCRHBPCRHR2 | |
| SCHEMBL29278097 | 0.90 | LOXL2 (0.48) | LOXL2CYP2A6RORCNSD2HRH3 | |
| SCHEMBL15831721 | 0.82 | HRH3 (0.59) | LOXL2CYP2A6RORCCRHBPCRHR2 | |
| SCHEMBL4406268 | 0.79 | HRH3 (0.50) | HRH3 | |
| SCHEMBL6263851 | 0.78 | LOXL2 (0.47) | LOXL2CYP2A6RORCCRHBPCRHR2 | |
| SCHEMBL19088665 | 0.78 | HRH3 (0.64) | LOXL2CYP2A6RORCNSD2HRH3 | |
| SCHEMBL6263660 | 0.77 | LOXL2 (0.45) | LOXL2CYP2A6RORCCRHBPCRHR2 | |
| SCHEMBL2201240 | 0.77 | RORC (0.53) | CYP2A6RORCHRH3 | |
| SCHEMBL541669 | 0.76 | HRH3 (0.59) | LOXL2CYP2A6RORCHRH3 | |
| SCHEMBL27909746 | 0.74 | CYP1A2 (0.52) | CYP2A6RORCIDO1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507175-A | Novel inhibitors of hypnotic proteins alpha and beta | 维沃里翁治疗股份有限公司 | 2022-05-17 | — | — | CN | disclosed |