Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | CES2 | O00748 | 3/20 | 0.56 |
| ▸ | CES1 | P23141 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | FADS1 | O60427 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282720 | 1.00 | MAPT (0.59) | MAPTGAAALDH1A1CES2CES1 | |
| SCHEMBL30293901 | 0.87 | CES2 (0.71) | MAPTGAAALDH1A1CES2CES1 | |
| SCHEMBL30790667 | 0.87 | MAPT (0.74) | MAPTGAAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL250099 | 0.87 | CES2 (0.71) | MAPTGAAALDH1A1CES2CES1 | |
| SCHEMBL112507 | 0.87 | MAPT (0.74) | MAPTGAAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL2703087 | 0.85 | KEAP1 (0.59) | MAPTGAAALDH1A1CES2CES1 | |
| Ammonia Solution, Strong SCHEMBL10992665 | 0.84 | MAPT (0.71) | MAPTGAAALDH1A1ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL11745887 | 0.84 | MAPT (0.71) | MAPTGAAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8764887 | 0.84 | MAPT (0.71) | MAPTGAAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL31574193 | 0.84 | CES2 (0.68) | MAPTGAAALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386118-B | Combination pharmaceutical agents as RSV inhibitors | 英安塔制药有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-114805133-A | Aryl chloroformate preparation method | 苏州星日化学有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-108200760-B | Benzodiazepine derivatives as RSV inhibitors | 英安塔制药有限公司 | 2022-04-01 | — | — | CN | disclosed |