Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDE8B | O95263 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18588084 | 1.00 | YTHDC1 (0.61) | YTHDC1NPC1RAB9ASMN1; SMN2PDE8B | |
| SCHEMBL20547440 | 0.97 | YTHDC1 (0.66) | YTHDC1NPC1RAB9ASMN1; SMN2PDE8B | |
| SCHEMBL29659514 | 0.97 | YTHDC1 (0.66) | YTHDC1NPC1RAB9ASMN1; SMN2PDE8B | |
| SCHEMBL29664965 | 0.89 | YTHDC1 (0.58) | YTHDC1NPC1RAB9ASMN1; SMN2FLT3 | |
| SCHEMBL18587539 | 0.89 | YTHDC1 (0.58) | YTHDC1NPC1RAB9ASMN1; SMN2FLT3 | |
| SCHEMBL30411235 | 0.89 | PDE8B (0.53) | YTHDC1NPC1RAB9ASMN1; SMN2PDE8B | |
| SCHEMBL20547447 | 0.87 | NPC1 (0.46) | YTHDC1NPC1RAB9ASMN1; SMN2PDE8B | |
| SCHEMBL18587526 | 0.87 | YTHDC1 (0.56) | YTHDC1NPC1RAB9ASMN1; SMN2FLT3 | |
| SCHEMBL29659492 | 0.87 | NPC1 (0.46) | YTHDC1NPC1RAB9ASMN1; SMN2PDE8B | |
| SCHEMBL30409865 | 0.86 | NPC1 (0.51) | YTHDC1NPC1RAB9ASMN1; SMN2PDE8B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341371-B1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIV PALACKEHO (CZ) | 2022-06-29 | — | — | EP | claimed |