Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30409865 | 0.97 | NPC1 (0.51) | PDE8BNPC1RAB9ASMN1; SMN2YTHDC1 | |
| SCHEMBL30411013 | 0.95 | PDE8B (0.49) | PDE8BNPC1RAB9ASMN1; SMN2YTHDC1 | |
| SCHEMBL30409376 | 0.90 | NPC1 (0.45) | PDE8BNPC1RAB9ASMN1; SMN2YTHDC1 | |
| SCHEMBL18588084 | 0.89 | YTHDC1 (0.61) | PDE8BNPC1RAB9ASMN1; SMN2YTHDC1 | |
| SCHEMBL29664987 | 0.89 | YTHDC1 (0.61) | PDE8BNPC1RAB9ASMN1; SMN2YTHDC1 | |
| SCHEMBL30411697 | 0.87 | NPC1 (0.49) | PDE8BNPC1RAB9ASMN1; SMN2YTHDC1 | |
| SCHEMBL29659492 | 0.87 | NPC1 (0.46) | PDE8BNPC1RAB9ASMN1; SMN2YTHDC1 | |
| SCHEMBL20547447 | 0.87 | NPC1 (0.46) | PDE8BNPC1RAB9ASMN1; SMN2YTHDC1 | |
| SCHEMBL20547440 | 0.86 | YTHDC1 (0.66) | PDE8BNPC1RAB9ASMN1; SMN2YTHDC1 | |
| SCHEMBL29659594 | 0.86 | YTHDC1 (0.55) | PDE8BNPC1RAB9ASMN1; SMN2YTHDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4178959-A1 | NITROGEN HETEROCYCLIC CYTOKININ DERIVATIVES, COMPOSITIONS CONTAINING THESE DERIVATIVES AND USE THEREOF | Univerzita Palackého v Olomouci (CZ) | 2023-05-17 | — | — | EP | disclosed |