Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.72 |
| ▸ | NUDT14 | O95848 | 2/20 | 0.71 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.71 |
| ▸ | LCK | P06239 | 6/20 | 0.66 |
| ▸ | ITK | Q08881 | 3/20 | 0.66 |
| ▸ | EGFR | P00533 | 2/20 | 0.66 |
| ▸ | JAK3 | P52333 | 2/20 | 0.66 |
| ▸ | SRC | P12931 | 7/20 | 0.62 |
| ▸ | LYN | P07948 | 5/20 | 0.61 |
| ▸ | FYN | P06241 | 5/20 | 0.61 |
| ▸ | FLT3 | P36888 | 4/20 | 0.61 |
| ▸ | PTK6 | Q13882 | 4/20 | 0.61 |
| ▸ | HCK | P08631 | 3/20 | 0.61 |
| ▸ | FGR | P09769 | 3/20 | 0.61 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.61 |
| ▸ | BRAF | P15056 | 3/20 | 0.61 |
| ▸ | BMX | P51813 | 3/20 | 0.61 |
| ▸ | YES1 | P07947 | 2/20 | 0.61 |
| ▸ | BLK | P51451 | 2/20 | 0.61 |
| ▸ | MAP2K5 | Q13163 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13861437 | 1.00 | BTK (0.72) | BTKNUDT14NUDT5LCKITK | |
| Hydrochloric Acid SCHEMBL29665759 | 0.99 | BTK (0.70) | BTKNUDT14NUDT5LCKITK | |
| SCHEMBL24458025 | 0.93 | BTK (0.69) | BTKNUDT14NUDT5LCKITK | |
| SCHEMBL16448087 | 0.90 | BTK (0.70) | BTKNUDT14NUDT5LCKITK | |
| SCHEMBL15916593 | 0.88 | BTK (0.67) | BTKNUDT14NUDT5LCKITK | |
| SCHEMBL27019885 | 0.87 | PIK3CD (0.72) | BTKNUDT14NUDT5LCKITK | |
| SCHEMBL22909341 | 0.87 | NUDT14 (0.72) | BTKNUDT14NUDT5LCKITK | |
| SCHEMBL28407363 | 0.86 | BTK (0.89) | BTKNUDT14NUDT5LCKITK | |
| SCHEMBL23409030 | 0.85 | NUDT14 (0.66) | BTKNUDT14NUDT5LCKITK | |
| SCHEMBL16448039 | 0.85 | BTK (0.64) | BTKNUDT14NUDT5LCKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175999-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2024-08-29 | — | — | WO | disclosed |
| US-20240018153-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2024-01-18 | — | — | US | disclosed |
| EP-4247794-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 Ontario, Inc. (CA) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022106902-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2022-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018153-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | ABCG2, ABCB1, ARSA | BTK 55/4885NUDT14 1332/4885NUDT5 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.