Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT14 | O95848 | 2/20 | 0.72 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.72 |
| ▸ | BTK | Q06187 | 16/20 | 0.70 |
| ▸ | LCK | P06239 | 6/20 | 0.70 |
| ▸ | ITK | Q08881 | 3/20 | 0.70 |
| ▸ | EGFR | P00533 | 2/20 | 0.70 |
| ▸ | JAK3 | P52333 | 2/20 | 0.70 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.58 |
| ▸ | PRKDC | P78527 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 6/20 | 0.58 |
| ▸ | BMX | P51813 | 3/20 | 0.58 |
| ▸ | SRC | P12931 | 6/20 | 0.57 |
| ▸ | LYN | P07948 | 5/20 | 0.57 |
| ▸ | FLT3 | P36888 | 4/20 | 0.57 |
| ▸ | PTK6 | Q13882 | 4/20 | 0.57 |
| ▸ | HCK | P08631 | 3/20 | 0.57 |
| ▸ | FGR | P09769 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409030 | 0.94 | NUDT14 (0.66) | NUDT14NUDT5BTKLCKITK | |
| SCHEMBL25069009 | 0.90 | NUDT14 (0.69) | NUDT14NUDT5BTKLCKITK | |
| SCHEMBL25069017 | 0.89 | NUDT14 (0.68) | NUDT14NUDT5BTKLCKITK | |
| SCHEMBL14643776 | 0.87 | BTK (0.76) | NUDT14NUDT5BTKLCKITK | |
| SCHEMBL14617791 | 0.87 | BTK (0.78) | NUDT14NUDT5BTKLCKITK | |
| SCHEMBL29665672 | 0.87 | BTK (0.72) | NUDT14NUDT5BTKLCKITK | |
| SCHEMBL13861437 | 0.87 | BTK (0.72) | NUDT14NUDT5BTKLCKITK | |
| SCHEMBL15517319 | 0.87 | BTK (0.81) | NUDT14NUDT5BTKLCKITK | |
| SCHEMBL16701418 | 0.87 | BTK (0.67) | NUDT14NUDT5BTKLCKITK | |
| SCHEMBL17090646 | 0.86 | BTK (0.80) | NUDT14NUDT5BTKLCKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018153-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2024-01-18 | — | — | US | disclosed |
| US-20240018153-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2024-01-18 | — | — | US | disclosed |
| EP-4247794-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 Ontario, Inc. (CA) | 2023-09-27 | — | — | EP | disclosed |
| CN-116745268-A | Benzenesulfonamide derivatives and uses thereof | 2692372安大略公司 | 2023-09-12 | — | — | CN | disclosed |
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2023-02-23 | — | — | US | disclosed |
| WO-2022106902-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2022-05-27 | — | — | WO | disclosed |
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | FURIN, PFAS, CFTR | NUDT14 1025/4885NUDT5 1619/4885BTK 305/4885 |
| US-20240018153-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | ABCG2, ABCB1, ARSA | NUDT14 1332/4885NUDT5 1313/4885BTK 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.