Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 5/20 | 0.77 |
| ▸ | MAPT | P10636 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666110 | 0.90 | MAPT (0.70) | SIRT6MAPTLMNARECQLALDH1A1 | |
| SCHEMBL29666080 | 0.89 | MAPT (0.77) | SIRT6MAPTLMNARECQLALDH1A1 | |
| SCHEMBL77148 | 0.87 | SIRT6 (1.00) | SIRT6MAPTLMNARECQLALDH1A1 | |
| SCHEMBL14892360 | 0.82 | SIRT6 (0.89) | SIRT6MAPTLMNARECQLALDH1A1 | |
| SCHEMBL29666078 | 0.81 | SIRT6 (0.82) | SIRT6MAPTLMNARECQLALDH1A1 | |
| SCHEMBL30059159 | 0.79 | LMNA (1.00) | SIRT6MAPTLMNARECQLALDH1A1 | |
| SCHEMBL25877527 | 0.79 | LMNA (0.94) | SIRT6MAPTLMNARECQLALDH1A1 | |
| SCHEMBL3109069 | 0.79 | LMNA (1.00) | SIRT6MAPTLMNARECQLALDH1A1 | |
| SCHEMBL29666126 | 0.79 | GAA (0.53) | SIRT6MAPTLMNARECQLALDH1A1 | |
| SCHEMBL3381562 | 0.78 | LMNA (0.97) | SIRT6MAPTLMNARECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111517-A1 | DEUTERIUM-MODIFIED THIENOPYRIDONE COMPOUND | 正大天晴药业集团股份有限公司 | 2022-06-02 | — | — | WO | disclosed |