Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 12/20 | 0.63 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.41 |
| ▸ | MARK4 | Q96L34 | 2/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | VHL | P40337 | 4/20 | 0.36 |
| ▸ | ELOC | Q15369 | 4/20 | 0.36 |
| ▸ | ELOB | Q15370 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17162049 | 1.00 | TBK1 (0.63) | TBK1IKBKEAURKBCDK2PDPK1 | |
| SCHEMBL23331357 | 0.96 | TBK1 (0.58) | TBK1IKBKEAURKBCDK2PDPK1 | |
| SCHEMBL21501554 | 0.94 | TBK1 (0.55) | TBK1IKBKEAURKBCDK2PDPK1 | |
| SCHEMBL22818571 | 0.89 | TBK1 (0.51) | TBK1IKBKEAURKBCDK2PDPK1 | |
| SCHEMBL22818563 | 0.86 | TBK1 (0.49) | TBK1IKBKEAURKBCDK2PDPK1 | |
| SCHEMBL22882524 | 0.86 | TBK1 (0.65) | TBK1IKBKEAURKBCDK2PDPK1 | |
| SCHEMBL23330925 | 0.84 | STK17A (0.50) | TBK1IKBKEAURKBCDK2STK17A | |
| SCHEMBL22818568 | 0.82 | TBK1 (0.44) | TBK1IKBKEAURKBCDK2PDPK1 | |
| SCHEMBL20201574 | 0.81 | TBK1 (0.79) | TBK1IKBKEAURKBCDK2PDPK1 | |
| SCHEMBL1284852 | 0.81 | TBK1 (0.61) | TBK1IKBKEAURKBCDK2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114262321-A | Bistable light-regulated small-molecule protein degradation agent, preparation method and application | 中国药科大学 | 2022-04-01 | — | — | CN | claimed |
| EP-4649963-A2 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2025-11-19 | — | — | EP | disclosed |
| CN-119591582-A | Imide-based proteolytic modulators and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-03-11 | — | — | CN | disclosed |
| US-20240299366-A1 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-09-12 | — | — | US | disclosed |
| CN-114262321-B | Bistable light-regulated small molecular protein degradation agent, preparation method and application | 中国药科大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-110612294-B | Human cerebulin ligands and bifunctional compounds comprising same | 阿尔维纳斯运营股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-115974840-A | Human cereblon ligand and bifunctional compound comprising same | 阿尔维纳斯运营股份有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-114262321-A | Bistable light-regulated small-molecule protein degradation agent, preparation method and application | 中国药科大学 | 2022-04-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299366-A1 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | CRBN, MDM2, UBE2N | TBK1 962/4885IKBKE 213/4885AURKB 1449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.