Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21588073 | 1.00 | TTR (0.39) | TTRALBMEN1KMT2A | |
| SCHEMBL17517026 | 0.77 | PDE2A (0.32) | TTR | |
| SCHEMBL7376575 | 0.77 | TTR (0.52) | TTRALBMEN1KMT2A | |
| SCHEMBL11645007 | 0.77 | TTR (0.52) | TTRALBMEN1KMT2A | |
| SCHEMBL29666465 | 0.75 | EGLN2 (0.33) | TTRALBMEN1KMT2A | |
| SCHEMBL21588076 | 0.75 | EGLN2 (0.33) | TTRALBMEN1KMT2A | |
| SCHEMBL21588237 | 0.73 | KIF11 (0.42) | — | |
| SCHEMBL1652055 | 0.71 | TTR (0.43) | TTRALB | |
| SCHEMBL14169297 | 0.71 | KIF11 (0.44) | TTRALB | |
| SCHEMBL17272656 | 0.70 | TRPV4 (0.32) | TTRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115089586-A | Compounds as nuclear transport modulators and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-112566902-B | Compounds as nuclear transport modulators and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2022-06-17 | — | — | CN | disclosed |