Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.48 |
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | REN | P00797 | 4/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.44 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 4/20 | 0.44 |
| ▸ | NPY1R | P25929 | 3/20 | 0.44 |
| ▸ | NPY2R | P49146 | 3/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666825 | 0.92 | CTSC (0.48) | MAPK8MAPK9MAPK10CALCRLGHSR | |
| SCHEMBL29387797 | 0.91 | CTSC (0.49) | MAPK8MAPK9MAPK10CALCRLGHSR | |
| SCHEMBL7174450 | 0.91 | CTSC (0.49) | MAPK8MAPK9MAPK10CALCRLGHSR | |
| SCHEMBL7174455 | 0.91 | CTSC (0.49) | MAPK8MAPK9MAPK10CALCRLGHSR | |
| SCHEMBL29666691 | 0.90 | MAPK8 (0.50) | MAPK8MAPK9MAPK10GHSRKEAP1 | |
| SCHEMBL1371049 | 0.90 | GHSR (0.51) | CALCRLGHSRKEAP1CTSCEED | |
| SCHEMBL1371051 | 0.90 | GHSR (0.51) | CALCRLGHSRKEAP1CTSCEED | |
| SCHEMBL31720924 | 0.90 | PRCP (0.41) | MAPK8MAPK9MAPK10CALCRLKEAP1 | |
| SCHEMBL29531541 | 0.90 | PRCP (0.41) | MAPK8MAPK9MAPK10CALCRLKEAP1 | |
| SCHEMBL29666759 | 0.90 | CTSC (0.46) | MAPK8MAPK9MAPK10GHSRKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332499-B2 | Cyclic peptides and methods of use thereof | ANPEP, NPR3, XPNPEP1 | MAPK8 2980/4885MAPK9 2784/4885MAPK10 2940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.