SCHEMBL296670

SCHEMBL296670

O=C(c1ccccc1)c1cccnc1C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.69
ALDH1A1 P00352 5/20 0.69
MAPT P10636 3/20 0.69
CYP3A4 P08684 1/20 0.69
ALOX15 P16050 1/20 0.69
TSHR P16473 1/20 0.69
BLM P54132 1/20 0.69
AGER Q15109 1/20 0.69
NPSR1 Q6W5P4 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
AKR1C3 P42330 1/20 0.57
DHODH Q02127 2/20 0.53
KMT2A Q03164 3/20 0.52
TDP1 Q9NUW8 1/20 0.50
GAA P10253 2/20 0.48
CYP1A2 P05177 1/20 0.47
NAPRT Q6XQN6 2/20 0.47
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7853761 0.98 KDM4E (0.67) KDM4EALDH1A1MAPTCYP3A4ALOX15
Oxalic Acid SCHEMBL31550428 0.96 KDM4E (0.65) KDM4EALDH1A1MAPTCYP3A4ALOX15
SCHEMBL7367595 0.91 KDM4E (0.67) KDM4EALDH1A1MAPTCYP3A4ALOX15
SCHEMBL187899 0.91 ALDH1A1 (0.55) KDM4EALDH1A1MAPTCYP3A4ALOX15
SCHEMBL9635664 0.88 KDM4E (0.80) KDM4EALDH1A1MAPTCYP3A4ALOX15
SCHEMBL7364079 0.86 KDM4E (0.61) KDM4EALDH1A1MAPTCYP3A4ALOX15
SCHEMBL7529815 0.86 KDM4E (0.61) KDM4EALDH1A1MAPTCYP3A4ALOX15
SCHEMBL6987666 0.86 ALDH1A1 (0.61) KDM4EALDH1A1MAPTCYP3A4ALOX15
SCHEMBL2212405 0.86 KDM4E (0.61) KDM4EALDH1A1MAPTCYP3A4ALOX15
SCHEMBL16534968 0.86 ALDH1A1 (0.61) KDM4EALDH1A1MAPTCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-119569604-A Latent alicyclic amide curing agent, preparation method and application thereof 万华化学集团股份有限公司 2025-03-07 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
CN-103923765-A Detergent Composition For Process Of Manufacturing Semiconductors And Displays COWON INNOTECH INC 2014-07-16 CN claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
JP-57055968-A None JP disclosed
US-12551555-B2 Compositions and methods for potentiating immune activity KUMQUAT BIOSCIENCES INC. (US) 2026-02-17 US disclosed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP disclosed
CN-119569604-A Latent alicyclic amide curing agent, preparation method and application thereof 万华化学集团股份有限公司 2025-03-07 CN disclosed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO disclosed
JP-S5755968-A PREPARATION OF COLORING MATTER HODOGAYA CHEM CO LTD 1982-04-03 JP disclosed
US-4259527-A OXIDATION OF SECONDARY ALCOHOLS TO KETONES WITH HYDROGEN PEROXIDE ALLIED CHEMICAL CORPORATION (US) 1981-03-31 US disclosed
US-4171313-A OF ALICYCLIC KETONES TO LACTONES, W-HYDROXY ACIDS AND ESTERS USING HYDROGEN PEROXIDE AS AN OXIDIZING AGENT ALLIED CHEMICAL CORPORATION (US) 1979-10-16 US disclosed
US-4002631-A HEAT-SENSITIVE COLOR FORMERS HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-11 US disclosed
US-3936564-A Pressure-sensitive copying paper containing lactone compounds of pyridine-carboxylic acid HODOGAYA CHEMICAL CO., LTD. (JA) 1976-02-03 US disclosed
US-3930672-A Pressure-sensitive copying paper containing lactone compounds derived from pyridine-carboxylic acid HODOGAYA CHEMICAL CO., LTD. (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS KDM4E 2134/4885ALDH1A1 3087/4885MAPT 2153/4885
US-12551555-B2 Compositions and methods for potentiating immune activity PTPRCAP, PTPN2, PTPRC KDM4E 2917/4885ALDH1A1 4675/4885MAPT 2945/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS KDM4E 2134/4885ALDH1A1 3087/4885MAPT 2153/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS KDM4E 2134/4885ALDH1A1 3087/4885MAPT 2153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.