SCHEMBL29669073

SCHEMBL29669073

OCc1c(F)ccc(F)c1Br

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 1/20 0.37
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
TAAR1 Q96RJ0 1/20 0.30
VEGFA P15692 2/20 0.30
EPAS1 Q99814 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16825606 1.00 DRD4 (0.37) DRD4CA2CA4TAAR1VEGFA
SCHEMBL31615014 0.84 DRD4 (0.33) DRD4
SCHEMBL28346668 0.84 DRD4 (0.38) DRD4CA2CA4TAAR1
SCHEMBL14448983 0.82 CA2 (0.32) DRD4CA2CA4
SCHEMBL19948162 0.82 CA2 (0.32) DRD4CA2CA4
SCHEMBL29864024 0.82 CA2 (0.32) DRD4CA2CA4
SCHEMBL1561647 0.81 TAAR1 (0.36) TAAR1
SCHEMBL31614958 0.78 CYP1A2 (0.34) DRD4
SCHEMBL22331222 0.78 CA2 (0.41) CA2CA4VEGFAEPAS1
SCHEMBL23835172 0.78 CYP11B1 (0.38) VEGFAEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112262142-B Benzenesulfonamide compounds and their use as therapeutic agents 泽农医药公司 2023-11-14 CN disclosed
CN-110325531-B Benzenesulfonamides and their use as therapeutic agents 泽农医药公司 2022-05-27 CN disclosed