Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19948162 | 1.00 | CA2 (0.32) | CA2CA4DRD4HDAC1HDAC6 | |
| SCHEMBL14448983 | 0.83 | CA2 (0.32) | CA2CA4DRD4HDAC1HDAC6 | |
| SCHEMBL16825606 | 0.82 | DRD4 (0.37) | CA2CA4DRD4 | |
| SCHEMBL29669073 | 0.82 | DRD4 (0.37) | CA2CA4DRD4 | |
| SCHEMBL29864532 | 0.81 | ACHE (0.31) | ACHE | |
| SCHEMBL19947979 | 0.81 | ACHE (0.31) | ACHE | |
| SCHEMBL1166843 | 0.78 | ENPP2 (0.33) | P2RX7ACHE | |
| SCHEMBL19810453 | 0.75 | NOTUM (0.33) | CA2CA4DRD4P2RX7ALDH1A1 | |
| SCHEMBL18070215 | 0.75 | CYP1A2 (0.35) | — | |
| SCHEMBL26547553 | 0.75 | ALDH1A1 (0.37) | CA2CA4DRD4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045039-A1 | INHIBITING HUMAN INTEGRIN ALPHA4BETA7 | Morphic Therapeutic, Inc. (US) | 2022-08-24 | — | — | EP | disclosed |