Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1780354 | 0.87 | ALDH1A1 (0.59) | ALOX15ALDH1A1BCHEPTGS2KDM4E | |
| 4,4-Diantipyrylmethane Monohydrate SCHEMBL3879841 | 0.86 | ALOX15 (0.62) | ALOX15ALDH1A1BCHEPTGS2KDM4E | |
| 4,4-Diantipyrylmethane Monohydrate SCHEMBL8664775 | 0.85 | ALOX15 (0.60) | ALOX15ALDH1A1BCHEPTGS2KDM4E | |
| SCHEMBL4324895 | 0.85 | ALOX15 (0.60) | ALOX15ALDH1A1BCHEPTGS2KDM4E | |
| SCHEMBL5718031 | 0.84 | ALOX15 (0.64) | ALOX15ALDH1A1BCHEPTGS2KDM4E | |
| SCHEMBL28049673 | 0.83 | BCHE (0.63) | ALOX15ALDH1A1BCHEPTGS2KDM4E | |
| SCHEMBL644930 | 0.82 | POLB (0.60) | ALOX15ALDH1A1BCHEPTGS2KDM4E | |
| SCHEMBL22689599 | 0.82 | KDM4E (0.63) | ALOX15ALDH1A1BCHEPTGS2KDM4E | |
| SCHEMBL1780443 | 0.82 | KDM4E (0.59) | ALOX15ALDH1A1BCHEPTGS2KDM4E | |
| SCHEMBL5209603 | 0.81 | ALOX15 (0.60) | ALOX15ALDH1A1BCHEPTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7770534-B2 | Changed condition indicator | THERMOPROX | 2010-08-10 | — | — | US | disclosed |
| US-20070151502-A1 | Changed condition indicator | THERMOPROX | 2007-07-05 | — | — | US | disclosed |