Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.55 |
| ▸ | PNP | P00491 | 2/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 3/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6622913 | 0.88 | FABP6 (0.55) | FABP6PNPNUDT1BRD4MMP12 | |
| SCHEMBL13135757 | 0.79 | HTT (0.50) | FABP6BRD4MEN1ALDH1A1KMT2A | |
| SCHEMBL6581218 | 0.77 | MEN1 (0.46) | FABP6PNPMEN1ALDH1A1KMT2A | |
| SCHEMBL14958067 | 0.76 | MEN1 (0.34) | FABP6MEN1ALDH1A1KMT2A | |
| SCHEMBL5679402 | 0.76 | NUDT1 (0.51) | FABP6PNPNUDT1BRD4RPS6KA3 | |
| SCHEMBL2541920 | 0.76 | CBFB (0.49) | FABP6PNPNUDT1MMP12RPS6KA3 | |
| SCHEMBL19954109 | 0.73 | KDM4E (0.42) | FABP6MEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL6856394 | 0.73 | PLAU (0.49) | FABP6PNPNUDT1BRD4MMP12 | |
| SCHEMBL6581987 | 0.72 | FABP6 (0.40) | FABP6PNPNUDT1BRD4MMP12 | |
| SCHEMBL393703 | 0.71 | FABP6 (1.00) | FABP6NUDT1MASP2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345681-B1 | Inhibitors of fibroblast growth factor receptor kinases | KINNATE BIOPHARMA INC. (US) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345681-B1 | Inhibitors of fibroblast growth factor receptor kinases | FGFR1, FGFR2, FGFR3 | FABP6 2400/4885PNP 1122/4885NUDT1 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.