Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14521789 | 0.98 | DNM1 (0.50) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| Bromide SCHEMBL231675 | 0.92 | ALDH1A1 (0.48) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL485968 | 0.90 | ALDH1A1 (0.50) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL16788930 | 0.89 | DNM1 (0.59) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| Bromide SCHEMBL11412610 | 0.88 | DNM1 (0.70) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| Iodide SCHEMBL20919878 | 0.88 | DNM1 (0.58) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| Bromide SCHEMBL231434 | 0.88 | DNM1 (0.59) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL16731588 | 0.87 | DNM1 (0.51) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| Bromide SCHEMBL231806 | 0.86 | DNM1 (0.43) | DNM1SMN1; SMN2MEN1KMT2ATP53 | |
| Bromide SCHEMBL232863 | 0.86 | DNM1 (0.43) | DNM1SMN1; SMN2MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112520756-B | Method for preparing SAPO-17 molecular sieve | 中国石油化工股份有限公司 | 2022-07-12 | — | — | CN | disclosed |