Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 7/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29670261 | 0.78 | ADRB1 (0.51) | ADRB1ADRB3ADRB2MAPTSMN1; SMN2 | |
| SCHEMBL11609943 | 0.78 | ADRB1 (0.76) | ADRB1ADRB3ADRB2MAPTSMN1; SMN2 | |
| SCHEMBL11450956 | 0.75 | MAPT (0.85) | ADRB1ADRB3ADRB2MAPTSMN1; SMN2 | |
| SCHEMBL2721052 | 0.75 | MAPT (0.67) | ADRB1ADRB3ADRB2MAPTSMN1; SMN2 | |
| SCHEMBL11602854 | 0.74 | MAPT (0.88) | ADRB1ADRB3ADRB2MAPTSMN1; SMN2 | |
| SCHEMBL11605988 | 0.73 | MAPT (0.65) | ADRB1ADRB3ADRB2MAPTSMN1; SMN2 | |
| SCHEMBL11546781 | 0.73 | MAPT (0.54) | ADRB1ADRB3MAPTSMN1; SMN2HTT | |
| SCHEMBL11620901 | 0.73 | MAPT (0.54) | ADRB1ADRB3MAPTSMN1; SMN2HTT | |
| SCHEMBL11237765 | 0.72 | ADRB1 (0.64) | ADRB1ADRB3ADRB2MAPTSMN1; SMN2 | |
| SCHEMBL15445654 | 0.72 | KMT2A (0.50) | SMN1; SMN2HTTMEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539129-B | Allylamine bifunctional compound and application thereof | 上海中医药大学附属龙华医院 | 2023-06-09 | — | — | CN | claimed |
| CN-114539129-B | Allylamine bifunctional compound and application thereof | 上海中医药大学附属龙华医院 | 2023-06-09 | — | — | CN | disclosed |
| CN-114539129-A | Allylamine bifunctional compound and application thereof | 上海中医药大学附属龙华医院 | 2022-05-27 | — | — | CN | disclosed |