⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11162106 | 0.75 | — | — | |
| SCHEMBL13274609 | 0.73 | — | — | |
| SCHEMBL7995431 | 0.73 | — | — | |
| SCHEMBL7954257 | 0.73 | — | — | |
| SCHEMBL16828847 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL3057710 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL8779932 | 0.70 | APLNR (0.47) | — | |
| SCHEMBL6998022 | 0.70 | — | — | |
| SCHEMBL13703390 | 0.70 | — | — | |
| SCHEMBL10458125 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267571-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES USEFUL IN TREATING CONDITIONS ASSOCIATED WITH CGAS | Novartis AG (CH) | 2023-11-01 | — | — | EP | claimed |
| WO-2022137082-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES USEFUL IN TREATING CONDITIONS ASSOCIATED WITH CGAS | NOVARTIS AG (CH) | 2022-06-30 | — | — | WO | claimed |
| EP-4267571-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES USEFUL IN TREATING CONDITIONS ASSOCIATED WITH CGAS | Novartis AG (CH) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022137082-A1 | PYRROLO[3,2-B]PYRIDINE DERIVATIVES USEFUL IN TREATING CONDITIONS ASSOCIATED WITH CGAS | NOVARTIS AG (CH) | 2022-06-30 | — | — | WO | disclosed |