SCHEMBL29672154

SCHEMBL29672154

N#Cc1cc(F)cc(C2CC2)c1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TRPM5 Q9NZQ8 1/20 0.39
FADS1 O60427 1/20 0.38
EGLN2 Q96KS0 1/20 0.37
DRD2 P14416 1/20 0.37
DRD3 P35462 1/20 0.37
PGR P06401 4/20 0.36
GRM2 Q14416 1/20 0.36
GRM5 P41594 2/20 0.36
AR P10275 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8860347 0.87 GRM2 (0.38) TRPM5FADS1DRD2DRD3PGR
SCHEMBL504920 0.86 FADS1 (0.39) TRPM5FADS1PGRGRM2GRM5
SCHEMBL16961551 0.80 EGLN2 (0.37) EGLN2DRD2DRD3
SCHEMBL504747 0.80 TRPM5 (0.34) TRPM5PGR
SCHEMBL16959742 0.80 NPY5R (0.30)
SCHEMBL7883408 0.78 TRPM5 (0.33) TRPM5FADS1PGRGRM5AR
SCHEMBL10285778 0.78 TRPM5 (0.35) TRPM5PGRGRM2
SCHEMBL3157843 0.78 NPY5R (0.39) GRM2
SCHEMBL15272344 0.77 TRPM5 (0.38) TRPM5FADS1PGRGRM5
SCHEMBL16412281 0.77 TRPM5 (0.38) TRPM5FADS1PGRGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4003974-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2022-06-01 EP disclosed